It’s super geeky, but I’m okay with that. It’s really fun to combine path knowledge with something that’s actually creative and pretty. And it’s sort of educational for my class…at the very least, they get a well-deserved break from the HOURS of lecture they have to sit through. Here are the end results (with a few high-yield things about each cell).
I’ve been really busy teaching this fall, so I haven’t been posting nearly as much as I’d like. I will be back to normal (ha) soon – but until then, I thought I’d share what we did in class yesterday. We’ve been learning about hematopathology (my favorite) – so I made cookies depicting some of the diseases we covered.
Sickle cells are seen, of course, in sickle cell anemia. They’re abnormally shaped because when sickle hemoglobin deoxygenates, it polymerizes, contorting the red cell into a sickle shape.
In some cases of bacterial infection, neutrophils develop little blue cytoplasmic inclusions, called DÃ¶hle bodies, which are chunks of revved-up rough endoplasmic reticulum.
Faggot cells contain TONS of Auer rods (faggot means bundle of sticks). They’re pathognomonic of acute promyelocytic leukemia, which has a t(15;17) that you should stick in your head somewhere.