A 44 year-old male with progressive weakness

A 44 year-old male presents with a several-week history of progressive weakness and visual changes. His family has noted a personality change over the past few months. An MRI shows multifocal, non-enhancing lesions involving the cortical white matter. A biopsy of one of the lesions is shown here. (more…)

A 52 year-old male with bloody diarrhea

A 52 year-old male presents with abdominal pain and bloody diarrhea which had a gradual onset over the last 3 weeks. He has lost 8 pounds during this period of time. A cecal biopsy is performed, and a representative section is shown here at two magnifications. (more…)

Can you solve this case?

Here’s a case that involves a very pretty cell. Once you know what this cell is, you won’t forget it – it’s that unusual and memorable!  (more…)