A 38 year-old male with advanced AIDS presents with severe headaches, fever and altered mental status, and dies several days later. An autopsy is performed, and a coronal section of the brain is shown here.
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Maybe I missed that pathology lecture, or maybe I was sleeping when the terms were discussed. (more…)
A 13 year-old male presents with a cerebellar mass. A biopsy is performed, and a representative section is shown here. (more…)
Q. This may be a silly question but…On the topic of anemia and increased RBC destruction, the lecture notes state that the spleen removes unusual shaped RBCs, causing anemia. (more…)

It would be cool if there was some medication that could lengthen one’s lifespan (while at the same time, keeping the skin plump and rosy). (more…)
Here is another case in our growing collection of unknown cases. These cases are like the ones you see when you’re a medical student or pathology resident rotating through surgical pathology. There’s always an “unknown” conference, and everyone dreads it (or at least I did). (more…)
Q. Could you please explain why the INR and PTT are not affected by the factor V Leiden mutation? (more…)

I’ve had a lot of emails about glomerulonephritis lately. Most people seem to want help simplifying the mechanisms and types of glomerular diseases (more…)

I’ve had quite a few questions about renal pathology lately. Some of you want to know how to differentiate renal diseases clinically (is it glomerular? or tubulointerstitial?) (more…)
A 45 year-old male presents with pulmonary emphysema and repeated bouts of hepatitis. On liver biopsy, there are numerous eosinophilic, globular inclusions, such as the one at the center of the field.
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