Systems Pathology | Pathology Student

Quick review: the 5 main intercellular junctions

Intercellular junctions are super common, especially between epithelial cells. There are 5 main types, and you should probably know a few of the basics about each. (more…)

A 60 year-old male with multiple lung nodules

A 60 year-old male with multiple peripheral lung nodules undergoes lung biopsy. A representative section is shown here. (more…)

A 52 year-old male with HIV and diarrhea

A 52 year-old male with HIV presents with profuse, watery diarrhea of 5 days’ duration. A biopsy of the small intestine is shown here. (more…)

Huntington disease

Huntington disease is a neurodegenerative disease that belongs to a category of genetic diseases known as trinucleotide repeat diseases. (more…)

How can an embolism cause a hemorrhagic infarct?

Q. I am confused as to how an embolism can cause a haemorrhagic infarct. To me, emboli are little chunks of clot that float around and get stuck in vessels. (more…)

Anti-TSH receptor antibodies

We just had our final exam in our pathology course, and someone had a good question on the following exam question: (more…)

A 52 year-old male with bloody diarrhea

A 52 year-old male presents with abdominal pain and bloody diarrhea which had a gradual onset over the last 3 weeks. (more…)

Leiomyoma vs. leiomyosarcoma

I love questions from our readers. If one person has the question, undoubtedly many others do as well. (more…)

A 58 year-old female with pelvic pain and menometrorrhagia

A 58 year-old female with a several-year history of pelvic pain and menometrorrhagia undergoes hysterectomy. Gross examination of the uterus reveals several rubbery white masses with a whorled appearance. (more…)

A 36 year-old female with a painless leg nodule

A 36 year-old female presents with this painless nodule on her lower leg. She notes that its size fluctuates, but that it is usually around 1 cm in diameter. When squeezed, the nodule dimples inward. (more…)