The Philadelphia chromosome in CML and ALL
Q. I have a question about the Philadelphia chromosome. The Philadelphia chromosome is present in chronic myeloid leukemia. (more…)
Richter’s transformation – prolymphocytes, large cells, or what?
Q. I have a quick question regarding Richter’s transformation in CLL. (more…)
Iron deficiency vs. anemia of chronic disease
Q. Are anemia of chronic disease and iron deficiency anemia technically both iron-deficient conditions? (more…)
Forward blood typing
Q. I have a question about blood typing. I understand that in forward typing, we use anti-A and anti-B antibodies. (more…)
Mono vs. acute leukemia
Q. I’m a medical student, and I wonder if you have some good tips about how to tell tell apart mononucleosis from AML on a blood smear? (more…)
Just how many B-cell lymphomas are there?
Q. Can you explain a bit about the classification of B-cell lymphoma? (more…)
Top 10 Anemias: Italian edition
Good news for our readers in Italy: The Top 10 Anemias to Know for Boards is now available in Italian! A big thank you to Francesco V. from Sicily for taking the time to translate the book for us.
How come the PT is normal in TTP?
Q. How come the PT and PTT are not increased in TTP and HUS? You have clots all over, so why don’t the coag tests go up like they do in DIC? (more…)
Heavy chain disease
Q. Why do light chains appear in the urine in mu heavy chain disease but not in alpha or gamma heavy chain diseases?
Why do you need the intrinsic pathway when you have the extrinsic pathway?
Q. I understand that hemophilia is caused by factor VIII or IX deficiency and both factors work in the intrinsic pathway. (more…)
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