Here is another case in our growing collection of unknown cases. These cases are like the ones you see when you’re a medical student or pathology resident rotating through surgical pathology. There’s always an “unknown” conference, and everyone dreads it (or at least I did). (more…)
Q. Could you please explain why the INR and PTT are not affected by the factor V Leiden mutation? (more…)

I’ve had a lot of emails about glomerulonephritis lately. Most people seem to want help simplifying the mechanisms and types of glomerular diseases (more…)

I’ve had quite a few questions about renal pathology lately. Some of you want to know how to differentiate renal diseases clinically (is it glomerular? or tubulointerstitial?) (more…)
A 45 year-old male presents with pulmonary emphysema and repeated bouts of hepatitis. On liver biopsy, there are numerous eosinophilic, globular inclusions, such as the one at the center of the field.
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